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    Flagyl (Metronidazole)Metronidazole (trade names include Flagyl; Amrizole; Anaerobex; Anaerobyl; Apo-Metronidazole; Arilin; Aristogyl; Bemetrazole; Dazomet; Dumozol; Elyzol; Flagyl-ER; Flazol; Klion; Metazol; MetroCream; Metroderme; MetroGel; Metrogyl; Metrolag; Metronidazol Normon; Metronide; Metrosa; Metrozine; NidaGel; Noritate; Nuvessa; PMS-Metronidazole; Protogyl; Riazole; Rosadan; Rosiced; Rozex; Supplin; Topmetro; Trichazole; Trichopol; Trichozole; Vagimid; Vandazole; Zidoval) is an antiinfective and antiprotozoal medication from imidazole derivatives pharmacological group for topical and systemic use. This medicine is indicated for the treatment of susceptible anaerobic bacterial and protozoal infections like respiratory tract, reproductive system, vaginal diseases, gastrointestinal tract, intraabdominal, skin and soft tissue, bone, joint infections. It is effective for the therapy of pelvic inflammatory disease, endocarditis, bacterial vaginosis (bacterial vaginitis), bacteremia, dracunculiasis (dracunculus), giardiasis, trichomoniasis, dientamoeba fragilis, diverticulitis, meningitis, nongonococcal urethritis, peritonitis, pouchitis, pseudomembranous colitis, amebiasis, pneumonia, aspiration pneumonia, Crohn's disease, Lemierre's syndrome, deep neck infections, dental abscess, Clostridium difficile colitis; liver abscesses, pleuropulmonary infections, brain abscesses caused by Entamoeba histolytica; Balantidium coli, Clostridial, Helicobacter Pylori infections; to prevent preterm birth associated with bacterial vaginosis; for surgical prophylaxis; prophylaxis of sexually transmissible diseases. Metronidazole is is widely used in veterinary to treat some infections dogs, cats, fish, other pets and animals. Flagyl works by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria.

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    General information about Metronidazole (Flagyl): [ref]

    Pharmacological and medical categories metronidazole:

  • 5-Nitroimidazole derivatives
  • Amebicides
  • Antiamoebics
  • Antibacterials
  • Antibiotics
  • Antiinfective medication
  • Antiprotozoal agents
  • Antiseptic skin cleansers
  • Local anti-infectives
  • Miscellaneous antibiotics
  • Preparations for vaginal conditions
  • Topical chemotherapeutics used in the treatment of dermatological diseases
  • Women's health


    The Anatomical Therapeutic Chemical (ATC) classification system codes:

  • Other bacterial intestinal infections - A04
  • Enterocolitis due to Clostridium difficile - A04.7
  • Amebiasis - A06
  • Other protozoal intestinal diseases - A07
  • Balantidiasis - A07.0
  • Giardiasis [lambliasis] - A07.1
  • Other specified protozoal intestinal diseases - A07.8
  • Streptococcal septicaemia - A40
  • Other septicaemia - A41
  • Other bacterial diseases, not elsewhere classified - A48
  • Infections with a predominantly sexual mode of transmission - A50-A64
  • Trichomoniasis - A59
  • Other spirochaetal infections - A69
  • Candidiasis - B37
  • Dracunculiasis - B72
  • Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere - B96.81
  • Mental and behavioural disorders due to use of alcohol - F10
  • Bacterial meningitis, not elsewhere classified - G00
  • Intracranial and intraspinal abscess and granuloma - G06
  • Acute and subacute endocarditis - I33
  • Phlebitis and thrombophlebitis of other sites - I80.8
  • Diseases of the respiratory system - J00-J99
  • Intracranial and intraspinal abscess and granuloma - G06
  • Bacterial pneumonia, not elsewhere classified - J15
  • Abscess of lung and mediastinum - J85
  • Pyothorax - J86
  • Diseases of the digestive system - K00-K95
  • Diseases of pulp and periapical tissues - K04
  • Gingivitis and periodontal diseases - K05
  • Stomatitis and related lesions - K12
  • Gastric ulcer - K25
  • Duodenal ulcer - K26
  • Crohn's disease [regional enteritis] - K50
  • Diverticular disease of intestine - K57
  • Peritonitis - K65
  • Other inflammatory liver diseases - K75
  • Abscess of liver - K75.0
  • Pouchitis - K91.850
  • Infections of the skin and subcutaneous tissue - L00-L08
  • Impetigo - L01
  • Cutaneous abscess, furuncle and carbuncle - L02
  • Cellulitis - L03
  • Other local infections of skin and subcutaneous tissue - L08
  • Local infection of the skin and subcutaneous tissue, unspecified - L08.9
  • Rosacea - L71
  • Diseases of the musculoskeletal system and connective tissue - M00-M99
  • Pyogenic arthritis - M00
  • Direct infections of joint in infectious and parasitic diseases classified elsewhere - M01
  • Osteomyelitis - M86
  • Diseases of the genitourinary system - N00-N99
  • Nonspecific urethritis - N34.1
  • Inflammatory diseases of female pelvic organs - N70-N77
  • Salpingitis and oophoritis - N70
  • Inflammatory disease of uterus, except cervix - N71
  • Inflammatory disease of cervix uteri - N72
  • Other female pelvic inflammatory diseases - N73
  • Other inflammation of vagina and vulva - N76
  • Acute vaginitis - N76.0
  • Subacute and chronic vaginitis - N76.1
  • Preterm labor - O60
  • Bacteremia - R78.81
  • Need for other prophylactic measures - Z29
  • Encounter for prophylactic surgery - Z40
  • Other medical care - Z51


    Pregnancy categories Metronidazole (Flagyl):

  • B2 - Australia
  • B - United States (No evidence of risk in humans)


    Salts and other forms used as active pharmaceutical ingredients (API):

  • Metronidazole Base
  • Metronidazole Benzoate
  • Metronidazole Hydrochloride
  • Metronidazole Hydrogen Succinate


    Synonyms, international and chemical names:

  • 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole
  • 1-(Beta-Ethylol)-2-methyl-5-nitro-3-azapyrrole
  • 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-
  • 1-Hydroxyethyl-2-methyl-5-nitroimidazole
  • 2-(2-Methyl-5-Nitro-1H-Imidazol-1-yl)Ethanol
  • 2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole
  • Benzoilmetronidazol
  • Benzoil Metronidazol
  • Benzoylmetronidazole
  • Imidazole-1-Ethanol, 2-Methyl-5-Nitro-
  • Methronidazole
  • Metronidasole
  • Metronidatsoli
  • Metronidazol
  • Metronidazolbenzoat
  • Metronidazole Benzoyl
  • Metronidazole HCl
  • Metronidazoli Benzoas
  • Metronidazolo
  • Metronidazols
  • Metronidazolum
  • MNZ


    Brands, generics, trade names in various countries:

  • Acuzole - Apotex; Pharmascript Pharmaceuticals
  • Adco-Metronidazole - Adcock Ingram; Al Pharm
  • Amrizole - Amriya Pharmaceutical Industries
  • Anaerobex - Gerot Pharmazeutika; G.L. Pharma
  • Anaerobyl - Pfizer
  • Anazol - Jazeera Pharmaceutical Industries
  • Apo-Metronidazole - Apotex; Nhan Tam; Pharmaforte
  • Arilin - Dr. August Wolff Arzneimittel; Alcina; Medika; Teva
  • Arilin Rapid - Dr. August Wolff Arzneimittel; Remedia; Solpharm
  • Aristogyl - Aristo Pharmaceuticals
  • Bemetrazole - Be-Tabs Pharmaceuticals
  • Benzoilmetronidazol - EMS Industria Farmaceutica; Sanofi-Aventis
  • Colpofilin - Dr. Lazar Laboratorio
  • Dazomet - Westmont Pharmaceuticals
  • Deflamon - Bieffe Medital; Societa Prodotti Antibiotici
  • Dumozol - Alpharma; Actavis; Aurovitas; Team Medica
  • Efloran - KRKA
  • Elyzol - Alpharma; C.T.S. Chemical Industries; Cabon-Denit; Chemomedica Medizintechnik und Arzneimittel; Colgate-Palmolive; Dumex; Minapharm Pharmaceuticals; Primal Chemical; Sime Darby Marketing; Stada
  • Entizol - Polpharma; Nam Sinh; Polfa Tarchomin
  • Epaq - 3M; More Pharma Corporation
  • Fish Zole Forte - Thomas Laboratories
  • Flagenase - Liomont Laboratorios
  • Flagyl - Sanofi-Aventis
  • Flagyl Forte - Sanofi-Aventis; Zuellig Pharma
  • Flagyl-ER - Sanofi-Aventis
  • Flagyl-S - Sanofi-Aventis; Four Star; IDS Group; Primecrown; Unither Liquid Manufacturing
  • Flagyl-V - Sanofi-Aventis
  • Flazol - Tabuk Pharmaceuticals; Bosch Pharmaceuticals; The Nile Company for Pharmaceuticals & Chemical Industries
  • Geloderm - SMB Farma Laboratorios
  • Ginkan - Baliarda Laboratorios
  • Grinazole - Septodont
  • Klion - Gedeon Richter; Medline; Pharmamagist
  • Lamblit - Novag Infancia
  • Medazol - Belupo
  • Metazol - Alliance Pharmaceuticals; Shalina Laboratories
  • MetroCream - Galderma
  • MetroCreme - Galderma
  • Metroderme - Galderma
  • MetroGel - Galderma; 3M; Derma UK; Dow Pharmaceutical Sciences; iNova Pharmaceuticals; More Pharma Corporation
  • Metrogyl - Unique Pharmaceutical Laboratories
  • Metrolag - Lagap Pharmaceuticals; Chalhoub Pharmaceuticals
  • Metrolet - Harsen
  • MetroLotion - Galderma
  • Metronidazol - Arena Group; Aristo Pharmaceuticals; B. Braun; Drossapharm; Genfar Laboratorios; Hexal; Jelfa Pharmaceuticals Works; Normon Laboratorios; Nycomed; Polpharma; Sandoz; Stada
  • Metronidazole - Actavis; Baxter; Fresenius; Generics UK; Nycomed; Pliva; Sandoz; Teva
  • Metronidazol-MK - MK Medicamentos; Tecnoquimicas
  • Metronidazolo - B. Braun; Fulton Medicinali
  • Metronidazolo Same - Savoma Medicinali
  • Metronide - Sanofi-Aventis; Clonmel Healthcare; Prodotti Laboratorio Farmaceutico
  • Metropast - Pasteur Laboratorios
  • Metroruboril - Isis Pharmaceuticals
  • Metrosa - Dr. August Wolff Arzneimittel; Linderma; Remedia
  • Metrovax - Vivax Pharmaceuticals
  • Metrozine - Pfizer; Monsanto Far East; Searle Pakistan
  • Metrozol - Arrow Pharma; Bosnalijek
  • Negazole - Gulf Pharmaceutical Industries, Julphar
  • NidaGel - 3M; Graceway Pharmaceuticals; Medicis Pharmaceutical Corporation; Valeant Pharmaceuticals
  • Nidagyl - Star Laboratories
  • Noritate - Sanofi-Aventis; Dermik Laboratories; Ebewe Pharma; Finn Vita Laboratorio; Ingens Laboratorios; Medibrands; Valeant Pharmaceuticals
  • Norzol - P & D Pharmaceuticals; Rosemont Pharmaceuticals
  • Nuvessa - Allergan; Actavis
  • Orvagil - Galenika
  • Otrozol - Comerciosa; Pisa Laboratorios
  • Ovufem - Bernabo Laboratorios
  • Perilox - Drossapharm
  • PMS-Metronidazole - Pharmascience
  • Promuba - Meprofarm
  • Protogyl - Xepa-Soul Pattinson; Apex Pharma Marketing; Grafton Pharmasia; Harmann Pharmaceutical Laboratories; Simed Laboratoires; Societe Arabe des Industries Pharmaceutiques; Tack Fung Medical Supplies
  • Riazole - Riyadh Pharma
  • Rosadan - Medimetriks Pharmaceuticals
  • Rosiced - Pierre Fabre
  • Rozex - Galderma
  • Supplin - Novartis; Biochemie; Sandoz
  • Topmetro - Tetramed Biotek
  • Trichazole - Aspen; Pharmacare
  • Trichopol - Polpharma; Akrikhin; Polfa Warszawa
  • Trichozole - Sanofi-Aventis; Mylan; Pacific Pharmaceuticals; Spencer Pharma
  • Tricofin - Raymos Laboratorios
  • Vagilen - Alfa Wassermann; Farmigea; Opalia Pharma Laboratories
  • Vagimid - Apogepha Arzneimittel
  • Vagizol - Kimia Farma
  • Vandazole - Teva; Upsher-Smith Laboratories
  • Zidoval - 3M; B & S Healthcare; iNova Pharmaceuticals; Meda; Metropolis Healthcare


    Pharmaceutical active ingredients used in medicine in combinations with metronidazole:


  • Acetylspiramycin
  • Amoxicillin
  • Benzalkonium Chloride
  • Ciprofloxacin
  • Clotrimazole
  • Dexamethasone
  • Diiodohydroxyquinoline
  • Diloxanide Furoate
  • Lansoprazole
  • Miconazole
  • Neomycin
  • Nystatin
  • Povidone-Iodine
  • Spiramycin
  • Tetracycline


    Some other medications in the same pharmacological classes:

  • Canesten Once Daily (Bifonazole)
  • Corsodyl (Chlorhexidine)
  • Abelcet (Amphotericin B)
  • Anaflex (Polynoxylin)
  • Bronchodex Pastilles (Domiphen)
  • Diflucan (Fluconazole)
  • Ebernet (Eberconazole)
  • Exelderm (Sulconazole)
  • Femcare (Clotrimazole)
  • Fungisan (Omoconazole)
  • Grifulvin (Griseofulvin)
  • Gyne-Lotrimin (Clotrimazole)
  • Gyno-Pevaryl (Econazole)
  • Gyno-Myfungar (Oxiconazole)
  • Gyno-Travogen (Isoconazole)
  • Gyno-Trosyd (Tioconazole)
  • Gynofort (Butoconazole)
  • Hexoral (Hexetidine)
  • Lamisil (Terbinafine)
  • Lomexin (Fenticonazole)
  • Lotrisone (Betamethasone; Clotrimazole)
  • Micetal (Flutrimazole)
  • Mintezol (Tiabendazole)
  • Mycelex-G (Clotrimazole)
  • Mycifradin (Neomycin)
  • Mycostatin (Nystatin)
  • Monistat (Miconazole)
  • Naska (Propenidazole)
  • Nizoral (Ketoconazole)
  • Noxafil (Posaconazole)
  • Pimafucin (Natamycin)
  • Sporanox (Itraconazole)
  • Sumycin (Tetracycline)
  • Tiberal (Ornidazole)
  • Tricandil (Mepartricin)
  • Triclose (Azanidazole)
  • Udder Balm (Oxyquinoline)
  • Vfend (Voriconazole)
  • Zalain (Sertaconazole)


    Here is a list of popular medications containing Metronidazole as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Flagyl
  • Capsules; Oral; Metronidazole 375 mg
  • Capsules; Oral; Metronidazole 500 mg
  • Cream; Topical; Metronidazole 1%
  • Cream; Topical; Metronidazole 10%
  • Gel; Topical; Metronidazole 0.75%
  • Injectable; Infusion; Metronidazole 5 mg / ml
  • Injectable; Injection; Metronidazole 5 mg / ml
  • Ovules; Vaginal; Metronidazole 500 mg
  • Suppositories; Vaginal; Metronidazole 1 g
  • Suppositories; Vaginal; Metronidazole 500 mg
  • Suspension; Oral; Metronidazole Benzoate 125 mg / 5 ml
  • Suspension; Oral; Metronidazole Benzoate 200 mg / 5 ml
  • Suspension; Oral; Metronidazole Benzoate 250 mg / 5 ml
  • Tablets, Film-Coated; Oral; Metronidazole 250 mg
  • Tablets, Film-Coated; Oral; Metronidazole 500 mg
  • Tablets; Oral; Metronidazole 200 mg
  • Tablets; Oral; Metronidazole 250 mg
  • Tablets; Oral; Metronidazole 400 mg
  • Tablets; Oral; Metronidazole 500 mg
  • Sanofi-Aventis
  • Abbott
  • Alvogen
  • DKSH
  • Ecosse Pharmaceuticals
  • Eczacibasi
  • Famar
  • Four Star
  • Fuji Seiyaku
  • GD Searle
  • Haupt Pharma
  • IDS Group
  • Institute of Pharmaceutical Research and Technology
  • KabiVitrum
  • Medicem
  • NeoFarma Pharmaceuticals
  • Nicholas Piramal
  • Odan Laboratories
  • Pfizer
  • Piramal Enterprises
  • Shionogi & Co.
  • Unither Liquid Manufacturing
  • Vitoria Laboratorios
  • Zambon
  • Zentiva
  • Zuellig Pharma
  • Flagyl-ER
  • Tablets, Extended Release; Oral; Metronidazole 250 mg
  • Tablets, Extended Release; Oral; Metronidazole 500 mg
  • Tablets, Extended Release; Oral; Metronidazole 750 mg
  • Sanofi-Aventis
  • GD Searle
  • Mova Pharmaceuticals
  • Pfizer
  • Metrogyl
  • Gel; Topical; Metronidazole 0.75%
  • Gel; Topical; Metronidazole 1%
  • Gel; Vaginal; Metronidazole 1%
  • Injectable; Infusion; Metronidazole 5 mg / ml
  • Injectable; Injection; Metronidazole 5 mg / ml
  • Pessaries; Vaginal; Metronidazole 500 mg
  • Suspension; Oral; Metronidazole 200 mg / 5 ml
  • Tablets, Film-Coated; Oral; Metronidazole 200 mg
  • Tablets, Film-Coated; Oral; Metronidazole 250 mg
  • Tablets, Film-Coated; Oral; Metronidazole 400 mg
  • Tablets, Film-Coated; Oral; Metronidazole 500 mg
  • Unique Pharmaceutical Laboratories
  • Alphapharm
  • Community Pharmacy
  • Dr. Reddy's Laboratories
  • Fresenius
  • Hexal
  • J.B. Chemicals & Pharmaceuticals
  • Lekar Pharma
  • Luen Cheong Hong
  • Morepen Laboratories
  • Rephco Laboratories
  • Societe des Industries Pharmaceutiques de Tunisie
  • Teva
  • Unexo Laboratories
  • Union Medical




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